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About the Author Tony Medrano is CEO and co-founder of LongevityPlan.AI, a platform that integrates performance and health data from athletes and leverages proprietary Cardiorespiratory Digital Twin technology, wearable data, and biomarker data to deliver personalized performance optimization and longevity recommendations to athletes, coaches, organizations, businesses, government, and the military

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Recently, it was also found that plant extracts can regulate microglia to express the M2 phenotype more than the M1 phenotype (Yang et al., 2017) to reduce neuroinflammation and nerve cell damage and to clear A (Figure 2)

However, metformin also exerts anticancer effects and is thought to do this through both AMPK-dependent and AMPK-independent mechanisms 116

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