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Nature 408 , 255262 (2000)

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Rutin can also prevent the activation of mast cells, which are immune cells that release histamine and other inflammatory mediators

Key challenges for clinical translation include the lack of consistent benefit, as large RCTs and systematic meta-analyses have failed to demonstrate efficacy of prebiotics/probiotics in ICU patients despite encouraging signals in individual studies ( 6 Limitations and future perspectives Despite growing recognition of ferroptosis in vascular injury, several fundamental limitations hinder its clinical translation

2006, 7: 8-doi:10.1186/1471-2156-7-8 Serajee FJ, Nabi R, Zhong H, Huq AHMM: Polymorphisms in xenobiotic metabolism genes and autism