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One theory why: Omega-3s easily cross the blood-brain barrier to interact with mood-regulating hormonesincluding dopamine and serotoninwhich may counteract depression

Renal cyst formation in Fh1-deficient mice is independent of the Hif/Phd pathway: roles for fumarate in KEAP1 succination and Nrf2 signaling

Mechanistically, melatonin acted independently of canonical melatonin receptors and instead reprogrammed ILC2 metabolism toward pentose phosphate pathway activity, enhancing NADPH generation and NRF2-dependent glutathione accumulation

Hepatology 52 , 21092117 (2010)

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