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Shen Y, Chow J, Wang Z, Fan G (2006)

Although these results are challenging to reconcile from a metabolic perspective, especially when considering that NKCC1 KO null mice display a range of developmental and functional abnormalities (Delpire et al., 1999

It is important to note that this concern is entirely theoretical -- no oncological adverse effects have been reported in the limited preclinical studies -- but the biological plausibility is high enough to warrant serious consideration

2.5 Clinical assessment of patients condition The severity of depressive disorder symptoms expressed as CDI scores (the Childrens Depression Inventory) was assessed every two weeks before and during the intervention by the study psychiatrist

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