The GSSG/2GSH redox system is fundamental in the cells and, together with other redox-active couples (including NADPH/NADP+, Trx-SH/Trx-SS), regulates and maintains the appropriate cellular redox status
Transport across the BBB may be facilitated by sodium-dependent transport system [76] or converting cysteine to cystine, which is subsequently exchanged with intracellular glutamate via the cystine-glutamate antiporter, and reduced back to cysteine for GSH production [115, 116]
Foods that may help support healthy glutathione levels include sulfur-rich vegetables such as broccoli, Brussels sprouts, cauliflower, kale, and cabbage
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As a supplement , glutathione is best taken in an intraoral or sublingual form as it is poorly absorbed in capsules or tablets