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Mixing them in a single solution for an extended period could lead to degradation, precipitation, or unforeseen chemical reactions that reduce their efficacy

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Phosphorylation of eIF2 leads to inhibition of general protein synthesis, but paradoxically increases the translation of selective mRNA such as ATF4 16

They generally target growth-hormone, recovery, or metabolic pathways, not reproductive hormones

J Biol Chem 285:4134841355 Smith AR, Shenvi SV, Widlansky M, Suh JH, Hagen TM (2004) Lipoic acid as a potential therapy for chronic diseases associated with oxidative stress