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The standard NHS pattern is a loading phase (injections on alternate days for up to two weeks), followed by maintenance

(These drugs are also known as Ozempic and Mounjaro when people take the same medications for diabetes.) And the amount of weight people lost with retatrutide matches or exceeds the amount of weight people lose when they have bariatric weight-loss surgery

1998 Jul;16(7):925

Connective Tissue Disease Scleroderma, CREST syndrome, and mixed connective tissue diseases are rare causes of reflux, but these should be considered in young women who have Raynaud phenomenon or subtle cutaneous features of scleroderma in the hands or face

While these benefits are promising and supported by animal studies, it's important to note that human clinical data is limited