The body can absorb between 55% and 97% of B12 from injections, compared to only about 1.3% from a high-dose oral supplement
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The Grading of Recommendation, Assessment, Development, and Evaluation (GRADE) tool was used to assess the certainty of the evidence for the two primary biochemical outcomesserum vitamin B12 concentration increase and homocysteine reductionacross all included studies, and separately for randomised controlled trials (RCTs) and observational studies
The primary advantage of B12 injections over supplements is the direct delivery of the nutrient to your bloodstream, as opposed to passing through your digestive tract
Apply a cold pack to the injection site before and after the injection to reduce pain