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Cryotherapy presents fewer concerns about long-term use

doi:10.1016/0024-3205(92)90504-i

Plus, reducing medication frequency may help older adults lose fat and retain muscle, according to his case series presented in November at the Obesity Week 2025 conference

What is measured in these rats and mice (and occasionally in small groups of human volunteers) is often not a hard endpoint like muscle strength or weight loss, but surrogate biomarkers: molecules in the blood that have an indirect link to a hard endpoint