These phytochemicals principally interacted with pivotal neuro-inflammatory signaling waterfalls, improved brain enzymatic activity, decreased nitrosative stress and RNS formation, improved brain antioxidant defense, regulated of pro-inflammatory-related gene expression, restored the activity of astrocytes and microglial cells, modulated brain transcription factors expression, alleviated COXs expression, enhanced expression of anti-inflammatory genes, and protected brain neuronal cells (248, 401, 402)
Correlations between the diurnal cortisol levels and objective cognitive performance were noted in several cognitive domains, such as memory, visuospatial, language and executive functions in the FM group (Supplementary Table S6)
doi: 10.1182/blood-2006-02-003681 71 OzcelikD.UzunH
Risks include hormone imbalances and side effects
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