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For example, several studies using proton magnetic resonance spectroscopy have reported reduced levels of N -acetyl aspartate, a marker of impaired mitochondrial energy production, in the brains of bipolar disorder patients compared with healthy controls [121,122,123,124,125]

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The rash can extend to the area around the nose and eyes, sometimes called periorificial dermatitis

FOXO4-DRI effectively counteracted doxorubicin-induced cell senescence and additionally mitigated doxorubicin-induced loss of body mass and elevated levels of aspartate aminotransferase (AST), contributing to the reduction of the hepatotoxicity of the chemotherapy agent [127]