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Additionally, we do not recommend these treatments for those who are pregnant or breastfeeding without explicit clearance from an OBGYN

For example, CYP2C9 and CYP2C19 variants (in particular CYP2C9 poor metabolizer genotypes), are associated with phenytoin-induced SJS/TEN even in the absence of HLA-B*1502 [46, 47]

doi: 10.1039/C9FO00333A

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There is no receptor overlap, no pathway competition, and no known pharmacokinetic interaction between them