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MTHFR symptoms often overlap with other health conditions, making them difficult to identify without testing

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In addition to energy production, mitochondria perform multiple other functions including Ca 2+ homeostasis [86, 87], generation of ROS [88], regulation of apoptosis [89], activation of endoplasmic reticulum-stress response [90], as well as other far-ranging sequelae of mitochondrial dysfunction [91]

Water retention: Some women notice slight puffiness or bloating, particularly in the hands and feet

Cancer metabolism: a therapeutic perspective