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Injection Site Reactions: Mild redness, swelling, or discomfort at injection sites (typically resolves quickly)

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These include findings such as the pro-convulsant effects of a hitherto unidentified endogenous substance containing copper [112, 230], or depolarization-induced co-release of endogenous copper with the major inhibitory neurotransmitter -aminobutyric acid (GABA) in different experimental models of nerve terminals in vitro (synaptosomal fraction) and ex vivo ( median eminence ) [225]