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Energy metabolism in the inner retina in health and glaucoma

Recent Initiatives Chapter 10

Intracellularly, CHAC1 enzymatically degrades GSH into 5-oxoproline and Cys-Gly, acting as a pro-ferroptotic execution signal by accelerating GSH exhaustion 151

The parasite does possess the common cellular redox buffer glutathione (GSH), however, its precursor amino acid cysteine can only be obtained from the host