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When to discard a vial Discard immediately if: The solution turns cloudy or develops visible particles You notice any color change from the original appearance The vial has been at room temperature for an extended period (check the pharmacy guidelines for your specific formulation) More than 28-30 days have passed since first puncture You suspect any contamination Tirzepatide is a large peptide molecule that degrades with heat, light, and bacterial contamination

doi: 10.1038/sigtrans.2017.23 273 NomanMZJanjiBKaminskaBVan MoerKPiersonSPrzanowskiPet al

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This mechanism underscores their definite origin in contrast to other types of EVs

For a deeper look at degradation mechanisms and optimal protocols, see our reconstituted peptide stability guide