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A meniscus tear is one of the most common knee injuries, affecting almost 1 million people annually in America

Passaia and Margispinheiro, 2015)

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In dermal fibroblast culture, the copper complex increased MMP-2 levels and MMP-2 mRNA an enzyme involved in remodeling the collagen scaffold during repair and also raised the secretion of the tissue inhibitors TIMP-1 and TIMP-2

Laboratory protocols should include appropriate controls and monitoring strategies to distinguish between beneficial elimination of harmful senescent cells and potential adverse effects on beneficial senescent cell populations