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In: Williams Textbook of Endocrinology

This compound is attracting attention for its ability to influence fat cell biology, energy metabolism, and even markers of healthy aging without relying on appetite suppression or stimulant-based mechanisms

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However, the combination has not been studied in clinical trials specifically for enhanced weight loss efficacy, so the B12 should be viewed as a nutritional supplement rather than a performance enhancement

Bacteroides thetaiotaomicron and Lactobacillus johnsonii generate fatty acids, particularly oleic acid and palmitic acid, regulate inflammatory immune responses, and eliminate Candida glabrata in the DSS-induced colitis mouse model ( Current antifungal drugs Currently, the first-line clinical antifungal drugs include polyenes (e.g., amphotericin B), azoles (e.g., fluconazole) and echinocandins (e.g., caspofungin) (Wiederhold, 2017