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Various tests of performance, multiple sleep latency, self-report, and nocturnal polysomnography have shown that DSIP exhibits this effect, also through its ability to improve REM sleep and regulate circadian and ultradian rhythms

the blend is preclinical and not approved for human use

These actions indicate that peptidergic transmitter systems including HGF/MET may hold critical pharmacological targets for treating the neurosequela of TBI

However, supplements can help address declining levels

Serious risks include pancreatitis (stop medication and seek immediate medical attention for severe abdominal pain radiating to the back), gallbladder disease, acute kidney injury (typically secondary to dehydration from gastrointestinal symptoms), and hypersensitivity reactions