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Future research priorities include understanding the long-term effects of senescent cell elimination on tissue homeostasis, regenerative capacity, and overall healthspan, providing foundation for developing sophisticated approaches to aging research and intervention strategies

Hoebeek) Thus far, the diseases in which we discussede.g., dystonia and strokehave been successfully treated in rodents by stimulating the cerebellar nuclei

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This study provides causal evidence that a mitochondrial and ER protein in specific neuronal types regulates anxiety- like and depression-like behaviours by coordinating mitochondrial function with neuronal structure and synaptic physiology

In contrast, the activities of control enzymes, LDH and GPx, showed no significant deviation from controls (Figure 5A)