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"I don't think they're doing it just for the price," said a young man, who said teenagers had other reasons for smoking or not

The 2008 US Guideline specifies that three combinations of medications are effective: A meta-analysis from 2018, conducted on 61 RCT, showed that during their first year of trying to quit, approximately 80% of the participants in the studies who got drug assistance (bupropion, NRT, or varenicline) returned to smoking while 20% continued to not smoke for the entire year (i.e.: remained sustained abstinent)

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Sixth, pooling the results of studies with different designs (observational and quasi-experimental) always requires caution