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In an increasing number of individuals with DMED who do not respond to medication, penile prosthesis implantation is being considered as a final option

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One example is the Fabp4 gene and its product fatty acid binding protein 4, which are highly expressed by Esm1 + ECs in the distal villus but absent in retinal tip cells 47,48 (Supplementary Fig

Neuromelanin confers the dark pigmentation that is produced from DA oxidation and is so characteristic of the SNpc appearance