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In our additional FC analysis, the smokers showed strongly reduced dACC FC, PCC FC and bilateral anterior insula FC than the controls, which was in accordance with previous literature 8,10,11

The volunteers underwent an incremental cycle exercise test and their heart, breathing and blood lactate rates were measured at each stage until they reached their maximum. Test results showed that both vaping and smoking groups had significantly reduced fitness levels and oxygen uptake by approximately 15%, according to the study

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