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NRF2 is the master antioxidant transcription factor that promotes ROS detoxification and KRAS -driven tumorigenesis by regulating the expression of SLC7A11, glutamate cysteine ligase subunits GCLC and GCLM, and other effectors [11, 55]

Well, here's an even to go even a little more, maybe an unpopular or something people don't talk about is they divide, in my opinion, to control

5-Fluorouracil resistant colon cancer cells are addicted to OXPHOS to survive and enhance stem-like traits

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