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In summary, GLPs work via multiple pathways, including enhancing disorders of glucose and lipid metabolism, antioxidation, anti-inflammation, anti-apoptosis, improving insulin resistance, and repairing the intestinal barrier

96,97 Moreover, the ME1 protein is hypophosphorylated at S336 and hyperacetylated at K337 by PGAM family member 5 and acetyl-CoA acetyltransferase, respectively, resulting in ME1 translocation from mitochondria to the cytosol, dimerization and activation, thus strongly promoting NADPH generation and tumorigenesis

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It can serve as a reservoir of reduced sulfur, interfacing with sulfur metabolism and biogenesis of sulfur-containing cofactors

Gavia-Garca G, Gonzlez-Martnez H, Miliar-Garca , Bonilla-Gonzlez E, de Rosas-Trejo los M, Knigsberg M et al (2015) Oxidative damage and antioxidant defense in thymus of malnourished lactating rats