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Most e-liquids use a form of nicotine known as freebase nicotine, which easily evaporates from e-cigarette aerosol, resulting in the release of nicotine from the aerosol droplets in the mouth, where it is slowly absorbed into the body

Jin J, Guo L, VonTungeln L, Vanlandingham M, Cerniglia CE, Chen H

Thus, when nicotine is no longer present, the pleasurable experience decreases and nicotine users feel the need for more nicotine in the body just to function normally, so they smoke another cigarette

Smokeless tobacco products are also associated with many health problems

Investing in youth tobacco control: a review of smoking prevention and control strategies, 2000