While 12 weeks of bright light exposure did not produce measurable improvements in sleep quality, glucose metabolism, or inflammatory markers, it significantly altered clock gene expression in peripheral blood mononuclear cells (PBMCs, specifically decreasing REV-ERB levels and increasing the REV-ERB/BMAL1 ratio)
However, doses of bisphenol-A higher than 100 M induce a substantial reduction the viability and the number of proliferating NSPCs in neurospheres, as well as the number of neurons and astroglial cells derived from them (Tiwari et al., 2015b)
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L.MehdizadehK.et al (2018)