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Although other hydroxylated metabolites derived from DHA have been identified in various biological fluids 20 , to our knowledge, 4-OXO-DHA has never been detected in animals fed n-3FA or in humans

The discovery of disease-causing gene alterations that code for multiple ubiquitinproteasome pathway proteins in Parkinson's disease has strengthened the relationship between the ubiquitinproteasome system and neurodegeneration

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