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Development of insulin resistance and obesity in mice overexpressing cellular glutathione peroxidase

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In a first study ( 2 O 2, GPX activity, glutathione disulfide (GSSG), cell proliferation, HA and pro-inflammatory cytokines were measured, in the presence or absence of selenium-(Methyl)-selenocysteine (SeMCys)

Numerous data indicate the importance of GSH and the GSH/GSSG ratio in the regulation of tumor cell viability, in the initiation of tumor development, progression, and drug resistance