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The results showed that the water-in-oil emulsion adjuvant formulation containing Quillaja saponaria-21 and monophosphoryl lipid A not only stabilized HBsAg and HBcAg for at least 12 weeks but also promoted dendritic cell activation in mice

SSRIs and tricyclics elevate KYNA by upregulating KAT expression in astrocytes and reduce 3-HK through downregulation of KMO [196]

Therefore, microbial- induced brain copper deficiency could be a fundamental scenario occurring in AD patients, which if true would greatly influence how we develop future therapies, a topic which we will discuss later

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