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no systemic diseases or medical conditions

The present study demonstrated that nicotine exposure via cigarette smoke downregulated GLT-1 gene and protein levels in the NAc, while tobacco smoke exposure decreased xCT gene and protein levels in the PFC and the NAc

A Brief History of Native Tobacco Use Tobacco has deep-rooted historical significance for Indigenous peoples in North America, with its use dating back thousands of years

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A study by Kessler et al