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Hepatocytes could also dedifferentiate into hepatic progenitor cells (HPCs, which are identified by markers such as SMA, SOX9, KRT19, EpCAM, and PROM1), and the proliferation and differentiation of hepatocyte-derived HPCs are closely associated with ductular reactions and portal fibrosis in liver injury (101)

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Upregulated GH receptor mRNA and protein in tendon fibroblasts Effect was dose-dependent and observed within 24 hours Provides a mechanistic link between BPC 157 and tissue growth/repair BPC 157 and blood vessels2019Vascular Review of BPC 157s vascular effects: promotes angiogenesis, protects endothelium, and counteracts vascular disruption in multiple injury models including thrombosis and ischemia-reperfusion