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Nijhout HF, Reed MC, Anderson DF, Mattingly JC, James SJ, Ulrich CM

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Although discovered over 50 years ago, intensive research into m 6 A was catalyzed by the identification of m 6 A-specific demethylases (e.g., FTO and ALKBH5), which established mRNA modifications as reversible and regulated epitranscriptomic marks [16, 36,37,38,39,40,41]