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C., Peng, S., Regan, M

doi:10.1002/art.38762 135

Inflammation Modulation: KPV exerts its effects by inhibiting the NF-kappaB pathway, a key regulator of inflammation

Just as HOOH (hydrogen peroxide) is more oxidized than HOH (O in H 2 O 2 has an oxidation number of 1- while the O in H 2 O has an oxidation number of -2), RSSR is the oxidized form (S oxidation number -1), and RSH is the reduced form (S oxidation number -2) of thiols