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While IGF1 LR3 itself has not been extensively studied in human clinical trials due to control factors, large research has been conducted using cell culture systems, animal models, and ex vivo tissue preparations

As a biomarker, it is used in the diagnosis and treatment of growth disorders, has been implicated in the prognosis and diagnosis of several cancers, and is used to aid in the identification of athletic enhancement from growth hormone use

The therapy needs to be tied to a specific, diagnosed medical condition

Anker, S