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Despite reduced smoking rates, tobacco is still a significant cause of premature death in the U.S., the CDC says

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Led by the French National Cancer Institute (INCa) and the French Institute for Public Health Research (IResP), it aimed to compare the chemical composition and toxicological effects of heated tobacco products, e-cigarette vapor, and traditional cigarette smoke

As you can see from the pictures of each box in the opened position, they do differ significantly in design