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Author Contributions HL conceived the study

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Scientists working on age related muscle changes have found the compound relevant for understanding cellular response to metabolic stress

Omega-3 Fatty Acids (Fish Oil) Why it may help: Reduces inflammation Supports skin barrier function May help reduce dryness and cracked lips May improve mood and help counter the inflammatory triggers of acne Evidence: Several small studies show Omega-3s improve skin hydration and reduce trans-epidermal water loss helpful when isotretinoin dries the skin

GHK-Cu for fine lines and wrinkles Fine lines form when the dermis gets thinner, and the surface folds more easily, and more set lines add repeated muscle movement and long-term UV injury on top of that