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Long-term studies in mice show that Epithalon administration significantly extended maximum lifespan by 12.3% and increased the lifespan of the last 10% of survivors by 13.3% compared to control groups, while showing no adverse effects on body weight or food consumption

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Genome-wide association study identifies common variants in SLC39A6 associated with length of survival in esophageal squamous-cell carcinoma

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Thus, oral iron therapy alone may be adequate in managing common iron-deficiency anemia, and this is reflected in standard clinical practice