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Class action plaintiffs and politicians described the Joe Camel images as a "cartoon" intended to advertise the product to people below the legal smoking age

[78] Varying nicotine concentrations are available and nicotine delivery to the user also varies based on different cartomizers, e-liquid mixtures, and power supplied by the battery

These cells were derived from primary human alveolar epithelial cells (AECs) isolated from resected lung tissue and subsequently immortalized using InscreeneXs CI-Screen technology, as described by Lipps et al