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In epithelial cells macropinocytosis is strongly connected to oncogenic activation and actin cytoskeleton rearrangements which are generally involved in cancer progression, and for this reason inhibition of macropinocytosis as means to prevent cholesterol uptake could be a useful approach in cancers that can activate it

The current report constitutes a meaningful advancement on the physiological role of DHARs

Intriguingly, polysome profiling indicated a significant impairment in the translation of CBS mRNA in DDX3X-deficient cells (Fig

M.KimM.-S.UmanahG.et al (2014)

Studies in aged rats further demonstrate Dihexa's potential for age-related cognitive decline