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If initial therapies are unsuccessful, transanal irrigation or barrier devices may be considered

Israetel has co-authored numerous peer-reviewed scientific papers on various topics

2017, Tenchov et al 2024) which can reduce an individuals quality of life and lead to complications that overburden the healthcare system (Aina et al 2021)

Materials and Methods Animals Study protocols were conducted in male albino Wistar rats, body weight 200 g, 13 weeks old, in-house bredanimal facility, Department of Pharmacology, School of Medicine, Zagreb, Croatia