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Both reactions can be catalysed by protein disulphide isomerase (PDI) and possibly other oxidoreductases that share common domains with PDI (for a recent review, see Ellgaard & Ruddock, 2005)

Activation of c-Jun-N-terminal kinase is required for apoptosis triggered by glutathione disulfide in neuroblastoma cells

10.3390/microorganisms10101887 107 ShawC

Activated immune-inflammatory and oxidative and nitrosative stress (IO&NS) pathways may underpin the somatic and mental symptoms of Long COVID because chronic fatigue syndrome, major depression and generalized anxiety disorder (GAD) are characterized by activated IO&NS pathways

USA 87 , 93789382 (1990)